Caspase 3 Silencing Inhibits Biomechanical Overload–Induced Intervertebral Disk Degeneration
نویسندگان
چکیده
منابع مشابه
Therapeutic Potential of Caspase 3 Silencing for Biomechanical Overload- induced Intervertebral Disc Degeneration
induced Intervertebral Disc Degeneration Katsuhisa Yamada, Hideki Sudo, Koji Iwasaki, Naoki Sasaki, Yusuke Kameda, Manabu Ito, Masahiko Takahata, Kuniyoshi Abumi, Akio Minami, Norimasa Iwasaki. Department of Orthopedic Surgery, Hokkaido University Graduate School of Medicine, Sapporo, Japan, Department of Advanced Medicine for Spine and Spinal Cord Disorders, Hokkaido University Graduate School...
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cluding cytokines, growth factors, enzymes, and enzyme inhibitors, in a paracrine or/and autocrine fashion.1,2 Anabolic regulators include polypeptide growth factors, such as insulin-like growth factor (IGF), transforming growth factor-β (TGF-β), and the bone morphogenetic proteins (BMPs).1–4 Other small molecules, such as the synthetic peptide of link protein, have also been reported to be reg...
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ژورنال
عنوان ژورنال: The American Journal of Pathology
سال: 2014
ISSN: 0002-9440
DOI: 10.1016/j.ajpath.2013.11.010